Main Article Content

Abstract

There are 421 blood bank in Indonesia, only 12 blood bank used NAT method to test transfusion transmitted disease. Whereas NAT is a moleculer test is recommended by WHO to detect window period. These study is to describe transfusion transmitted disease using NAT and CLIA method on exposure to Hepatitis B virus in Red Cross Semarang City periode April-December 2019. The result of NAT and CLIA are diviaded to two groups, reactive or non-reactive on exposure of Hepatiti B virus. The method used in this research is a descriptived method which is analyzed with univariat. The variabel was obtained from medical record from Red Cross Semarang city which consist of reactive or nonreactive in NAT and CLIA as much 6.931 population. The samples used in this study are 100 samples, using the purposive sampling technique with predefined criteria. In 100 samples, we found 19 reactive test with NAT methods, 17 reactive test with NAT and CLIA and finally found 64 non reactive with NAT and CLIA. From the population of 6.931, only 36 is reactive with NAT only, or both NAT and CLIA (19 reactive on NAT methods and 17 reactive on NAT and CLIA methods). As the result only 0,5% is reactive, so NAT and CLIA are important test for blood safety requirements.

Keywords

NAT method, CLIA method, Hepatitis B

Article Details

How to Cite
Puspita, R. (2021). Overview of Hepatitis B Virus Exposure on NAT and CLIA Blood Examination Methods at PMI Semarang City. International Journal of Seocology, 3(1), 001–006. https://doi.org/10.29040/seocology.v3i1.37

References

  1. Baruah, S., & Pal, L. (2019). Seven years experience in NAT testing of blood donors in a tertiary care centre.
  2. Bustami, A., & Anita, A. (2020). Pencegahan Transmisi Virus Hepatitis B pada Masa Perinatal. Jurnal Ilmiah Keperawatan Sai Betik, 15(2), 145-156.
  3. Halimah, N., & Satria, A. P. (2015). Analisis Praktik Klinik Keperawatan pada Pasien Diabetes Melitus Tipe II, Hepatitis B, dan Dekubitus Grade 2 Terhadap Pemberian Posisi Miring 30 Derajat di Ruang High Care Unit RSUD Abdul Wahab Syahranie Samarinda Tahun 2015.
  4. Hans, R., & Marwaha, N. (2014). Nucleic acid testing-benefits and constraints. Asian journal of transfusion science, 8(1), 2.
  5. Khumaedi, A. I., Gani, R. A., & Hasan, I. (2016). Pencegahan transmisi vertikal hepatitis B: fokus pada penggunaan antivirus antenatal. Jurnal Penyakit Dalam Indonesia, 3(4), 225-231.
  6. Laporan Tahunan Hasil Pemeriksaan IMLTD Tahun 2018 UDD PMI Kota Semarang
  7. Laporan Tahunan Hasil Pemeriksaan IMLTD Tahun 2019 UDD PMI Kota Semarang
  8. Mathur, A., Dontula, S., & Jagannathan, L. (2017). A study of centralized individual donor nucleic acid testing for transfusion transmitted infections to improve blood safety in Karnataka, India. Global Journal of Transfusion Medicine, 2(1), 24.
  9. Murniasih, A. (2018). Perbedaan Kadar HBsAg Sampel Serum dan Plasma Metode CLIA Pada Pendonor (Doctoral dissertation, Universitas Muhammadiyah Semarang).
  10. Plaß, D., Mangen, M. J., Kraemer, A., Pinheiro, P., Gilsdorf, A., Krause, G., ... & Kretzschmar, M. E. E. (2014). The disease burden of hepatitis B, influenza, measles and salmonellosis in Germany: first results of the burden of communicable diseases in Europe study. Epidemiology & Infection, 142(10), 2024-2035.
  11. Pramudya, G. A. (2020). Korelasi Kadar hs-CRP (High-Sensitivity C-Reactive Protein) dengan Jumlah Sel Monosit Pada Penderita Hepatitis B (Doctoral dissertation, Poltekkes Kemenkes Surabaya).
  12. Sari, A. I., Windi, R. R., & Mutiara, H. (2019). 1. Kementrian Kesehatan Republik Indonesia. Pusat data dan informasi tuberkulosis. Jakarta: InfoDATIN; 2018. 2. Sharma SK, Mohan A, Sharma A. Miliary tuberculosis: A new look at an old foe. J Clin Tuberc. 2016; 3 (1): 13–27. 3. Ray S. Diagnosis and mana. Medical Profession Journal of Lampung, 9(2), 374-378.
  13. Shrivastava, M., & Mishra, S. (2017). Nucleic Acid Amplification testing (NAT): An innovative Diagnostic approach for enhancing blood safety. J Lab Med, 6.
  14. Sulaiman, M. A., Hutagalung, S. D., Ain, M. F., & Ahmad, Z. A. (2010). Dielectric properties of Nb-doped CaCu3Ti4O12 electroceramics measured at high frequencies. Journal of alloys and compounds, 493(1-2), 486-492.
  15. World Health Organization. (2015). Manual for the development and assessment of national viral hepatitis plans: a provisional document. World Health Organization.
  16. World Health Organization. (2017). Global hepatitis report 2017. World Health Organization.